Tofisopam is a medications used for the treatment of anxiety disorder and its related psychological and physical symptoms.
It is also indicated for the treatment of alcohol withdrawal, and is prescribed in a dosage of 50 to 300mg per day divided into three doses. Peak plasma levels are attained two hours after an oral dose.
Tofisopam is not reported as causing dependence to the same extent as other benzodiazepines, but is still recommended to be prescribed for a maximum of 12 weeks.
It is also claimed to be a PDE10 selective inhibitor, which may provide an alternative mechanism of action for its various therapeutic effects, and this action has been proposed to make tofisopam potentially useful as a treatment for schizophrenia.
